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Can Wegovy help type 2 diabetes?

Can Wegovy help type 2 diabetes?

The short answer? Yes, Wegovy can help type-2 diabetes – but there are things you need to be aware of when using Wegovy for the condition.

Semaglutide, the active ingredient in Wegovy, can help increase how much insulin your body makes when your blood sugar levels are high. It can also help to reduce the amount of sugar your liver makes, and slow down how long it takes for food to leave your stomach. This helps to keep your blood sugar levels in check.

Alexandra Cristina Cowell
Medically reviewed by
Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
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Medically reviewed by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
on Mar 05, 2025.
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Alexandra Cristina

Last updated on Nov 07, 2025.

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icon tickWegovy is a weight loss treatment, but its active ingredient was originally developed for type 2 diabetes.

icon tickIt helps manage diabetes by increasing the insulin released when your blood sugar levels are high.

icon tickIt can also lower the risk of cardiovascular events associated with type 2 diabetes.

icon tickWegovy could be a good option if you have overweight or obesity and have type 2 diabetes.

Understanding type 2 diabetes

Type 2 diabetes is a condition where the levels of sugar in your blood get too high, and your body can’t manage it on its own. This is because your body doesn’t produce enough of a hormone called insulin, or your body’s cells don’t respond properly to insulin.

Normally, insulin moves sugar out of your blood and into your cells to provide them with energy. But, if you have type 2 diabetes, too much sugar stays in your bloodstream. High blood sugar levels can cause symptoms like fatigue, needing to urinate a lot, and thirst that isn’t quenched by drinking. If it’s left unchecked and your blood sugar levels stay too high for too long, it can lead to serious health problems that affect your circulation, eyes, heart, feet, and nerves.

What is Wegovy?

Wegovy is a type of medication known as a glucagon-like peptide-1 (GLP-1) receptor agonist. This means it mimics the natural GLP-1 hormone that’s produced by the body after eating. While Wegovy is only approved as a weight loss medication, its active ingredient (semaglutide) was originally approved as a type-2 diabetes medication under the brand Ozempic. After weight loss was reported as a common side effect of Ozempic, a different version of semaglutide was approved as a weight loss treatment, which is how we ended with Wegovy.

So if you’re looking for a medication to keep your type-2 diabetes in check, and you’re living with overweight or obesity, Wegovy could help manage both in one treatment.

How does Wegovy work?

By mimicking how the natural GLP-1 hormone produced by your body works, Wegovy helps to reduce your blood sugar levels, limit the amount of sugar put into your bloodstream, and help reduce your appetite and cravings for sugary food.

It does this by activating GLP-1 receptors, which increases the amount of insulin released by your body when your blood sugar levels are high (like just after you’ve eaten). It also helps slow the release of glucagon, a hormone that counteracts insulin that’s released by your pancreas when your blood sugar levels drop. It tells your liver to convert stored sugar (glycogen) into usable sugar (glucose) and release it into your bloodstream. This should help to bring your blood sugar levels back down when they increase, and help stop your body from raising them again.

Wegovy also affects your brain to lessen feelings of hunger and cravings for specific foods, while also increasing how satisfied you feel after eating. This should help limit spikes in your blood sugar levels from eating a carbohydrate- or sugar-heavy meal.

Benefits of Wegovy for type 2 diabetes

While Wegovy can offer additional benefits to weight loss for people with diabetes, it’s important to remember that everyone reacts differently to treatment – and what works for someone else might not work for you (and vice versa). This is why you should always follow your healthcare provider’s instructions when taking Wegovy, and only ever take the dose they’ve set for you.

Following your healthcare provider’s guidance ensures that you’re using the dose of Wegovy that offers the most benefit with the smallest risk of side effects. If you up your dose without speaking to your healthcare provider, or skip a dose and go straight to a higher dose, you’re far more likely to get side effects that mean you have to stop treatment.

But research suggests Wegovy can help improve blood sugar control in the long term. A 2023 study reported that treatment with semaglutide (the active ingredient in Wegovy) resulted in improved blood sugar control in people with type 2 diabetes. These improvements were observed after 180 days of treatment and sustained for up to three years – suggesting Wegovy could be a suitable option for long-term diabetes management alongside weight loss.

Weight loss

Wegovy helps you lose weight by reducing your appetite and slowing down how quickly food passes through your digestive system. This means you feel satisfied for longer after eating, and should have fewer cravings – which helps you eat less and promotes weight loss.

Losing weight with Wegovy can help improve blood sugar control, and could even help to achieve total remission of type 2 diabetes. Evidence suggests that losing just 5% of your body weight can improve your blood sugar levels, and losing around 33 pounds (15 kg) can often result in total remission of type 2 diabetes – but this isn’t recorded very often right now. This could be because people simply don’t think that remission through weight loss is achievable, but Wegovy can help encourage weight loss while also providing additional benefits for type 2 diabetes.

Improved blood sugar control

Losing weight can help improve your blood sugar control by reducing fat around your liver and pancreas. Too much fat stored in and around these organs increases your risk of insulin resistance, which can lead to type 2 diabetes. While insulin resistance can affect people who aren’t living with overweight or obesity, it’s more commonly linked with those who are. This is where Wegovy can help.

Using Wegovy for weight loss can help to reduce the risk of fat buildup in the liver, and studies report that semaglutide is an effective and well-tolerated treatment for nonalcoholic fatty liver disease. Increasing your physical activity is also really important when using Wegovy, and upping your activity levels is another way to help treat insulin resistance. Combining Wegovy with a healthy diet and regular exercise should reduce body fat, and increase how sensitive your cells are to insulin. Insulin sensitivity also increases for at least 16 hours after exercising – meaning regular workouts can help improve your blood sugar control in both the short and long term.

Reduced risk of cardiovascular events

The benefits of Wegovy for those with type 2 diabetes don’t just end with improved blood sugar control, either. Clinical trials show that semaglutide can substantially reduce heart failure events and death from cardiovascular events in high-risk populations with type 2 diabetes. In a study where 3,533 people took either semaglutide or a placebo, those who took semaglutide had fewer heart cardiovascular problems compared to those who took the placebo.

Improved quality of life

Using Wegovy to help with weight loss and blood sugar control can lead to improved well-being and overall health, too.

High blood sugar levels can damage your kidneys, so keeping them in check can reduce your risk of kidney disease. This happens because high blood glucose damages your arteries, which increases blood pressure. Increased blood pressure can then damage your kidneys, causing kidney disease and failure. If left untreated, this can create a cycle of damage, where kidney problems further increase your blood pressure, which further damages your kidneys. By helping to manage your blood glucose, Wegovy can relieve pressure on your blood vessels and kidneys and help keep them healthy.

Losing weight with Wegovy can also lower your blood pressure, helping keep your kidneys healthy. It’s really important you make changes to your diet and get in the habit of regular exercise to lose weight with Wegovy. Studies suggest that exercise alone can reduce your blood pressure, and eating a low-fat diet high in sources of fiber (like fruit and veggies) can help improve blood pressure even more. So the same lifestyle changes you’ll be making to help lose weight with Wegovy can improve your cardiovascular health, and lower your risk of kidney disease.

What about potential side effects?

Like any medication, there’s a chance you’ll experience some side effects on Wegovy. Most of these side effects can affect anyone, whether they have type 2 diabetes or not.

As Wegovy slows down the speed your stomach empties, it’s really common to experience some nausea when you move to a higher dose of treatment. The good news is it typically passes within a few days increasing your dose of Wegovy. It’s important to drink plenty of water when you’re using Wegovy, as nausea and vomiting can cause you to become dehydrated – and this can make other Wegovy side effects like headaches even worse.

Wegovy can also cause complications with diabetic eye disease – so it’s really important to speak to your doctor if you have diabetes and your vision changes at all during treatment.

Is Wegovy right for you to help manage type 2 diabetes?

Wegovy isn’t a medication for type 2 diabetes – it’s approved as a weight loss treatment to be used alongside a good diet and regular exercise to help with weight loss. But if you’re living with overweight or obesity and type 2 diabetes, Wegovy could be an option to help manage both conditions. Speak to a healthcare provider about your weight loss and diabetes treatment options if you’re interested in using Wegovy for type 2 diabetes and weight loss.

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