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Reviewed on June 05, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on June 05, 2028.
Last updated on Jun 30, 2025.
A combined pill with added iron. Supports your body during your period.
Loestrin Fe is a combined oral contraceptive that prevents pregnancy. It also includes iron in the inactive pills, which can help to boost the iron lost during your period. It’s over 99% effective when used correctly.
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Loestrin Fe is a combined birth control pill. It’s called that because it contains two hormones, progestin and estrogen. The inactive pills also contain iron (not enough to treat an iron deficiency, but enough to help during your period).
There are several types of Loestrin Fe available, so you can find a strength that’s right for you. We offer Loestrin Fe 1/20 and Lo Loestrin Fe.
What doses of Loestrin Fe are there?
There are two doses of Loestrin Fe: Loestrin Fe 1/20 and Loestrin Fe 1.5/30. Loestrin Fe 1/20 has 1mg norethindrone acetate and 20mcg ethinyl estradiol. Loestrin Fe 1.5/30 is the same but with slightly more of each active ingredient: 1.5mg of norethindrone acetate and 30mcg of ethinyl estradiol.
There is also a low-dose version called Lo Loestrin Fe, which contains the lowest daily dose of estrogen available in hormonal birth control.
How does Loestrin Fe work?
The hormones in Loestrin Fe work in three ways. They stop ovulation, so no eggs are released to be fertilized, and they thicken the mucus in your cervix, making it harder for sperm to travel through. Finally, they change the thickness of the uterine lining – which can also mean your period will be shorter and lighter.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on June 05, 2025. Next review due on June 05, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Take a pill once a day, at the same time every day. Follow the order as directed on your pill pack.
What should I do if I take too much Loestrin Fe?
If you think you’ve taken too much Loestrin Fe, speak to a medical professional as soon as possible. If you’re experiencing any severe side effects, call 911 or go to your nearest emergency room.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on June 05, 2025. Next review due on June 05, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
What happens if I miss a pill?
Answer:
If you miss one Loestrin Fe pill, take it as soon as you remember. This could mean taking two in one day. After that, take one pill a day like normal.
We recommend using a back-up birth control, like condoms, for a week to make sure you’re adequately protected.
How effective is Loestrin Fe?
Answer:
When taken correctly, Loestrin Fe 1/20 is around 99% effective[3] while Lo Loestrin Fe is around 98%.[4] This means that if 100 women took Loestrin Fe 1/20 daily for a year, less than 1 woman would become pregnant.
With ‘typical’ use (missing the occasional pill), the effectiveness is a little lower, around 93%.
Can I get Loestrin Fe through private health insurance?
Answer:
Most private healthcare plans in the USA should cover Loestrin Fe, but each plan can be different. It’s best to check the plan you’re on to see if it’s covered.
Many plans also stipulate that you need to obtain treatment from specific providers, so you should also check this before buying treatment, to make sure the provider you’re getting it from is included in your coverage.
Does Loestrin Fe help with acne?
Answer:
Loestrin Fe can help with acne.[2]Â The hormones in the pill can decrease how much oil your skin produces, which can help control acne.
If you want birth control that can also treat acne, let the doctor know during your consultation so they can recommend the best option.
Does Loestrin Fe stop your period?
Answer:
Loestrin Fe can stop your period, but it’s not a guarantee. It’s likely you’ll have a shorter and lighter period while taking hormonal birth control, but it won’t necessarily stop.
There are some forms of birth control that are more effective at stopping periods than others, so let the doctor know during your consultation if you want a pill that can help.
Is Loestrin Fe generic?
Answer:
No, Loestrin Fe is not a generic birth control. However, there are other versions of it, which means they have the same active ingredients in the same quantities:
Aurovela Fe 1/20, 1.5/30
Blisovi Fe 1/20, 1.5/30
Gildess Fe 1/20, 1.5/30
Hailey Fe 1/20, 1.5/30
Junel Fe 1/20, 1.5/30
Microgestin Fe 1/20, 1.5/30
Larin Fe 1/20, 1.5/30
Does Loestrin Fe cause weight gain?
Answer:
While we’ve all heard about weight gain associated with the pill, there haven’t been any scientific studies that were able to prove a connection.[1] That’s because there are so many different elements that go into how much we weigh, and weight fluctuates a little every day.
There are two things that hormonal birth control can do that look like weight changes from the outside. Some pills can cause water retention, aka bloating — you’ve probably experienced this already during your cycle, and know what it’s like. Birth control pills can also impact your appetite, which might ultimately change your weight. The important thing to remember is that weight doesn’t magically appear or disappear. If you’re experiencing an uncomfortable amount of bloating with your birth control or noticing that it’s impacting your appetite, it might be time to try a different prescription. We’re here to help.
What is Lo Loestrin Fe?
Answer:
Lo Loestrin Fe is the lowest daily dose of estrogen available. The first 24 pills are active pills with 1mg norethindrone acetate and 10mcg ethinyl estradiol. The next two pills are also active and contain 10mcg of ethinyl estradiol. The last two are inactive pills with an iron supplement.
Loestrin Fe 1/20 vs Blisovi 24 Fe: which is better?
Answer:
Blisovi 24 Fe is a generic version of Loestrin 24 Fe, which has been discontinued. Loestrin Fe 1/20 and Blisovi 24 Fe have the same amount of hormones in the active pills: 1mg of norethindrone acetate and 20mcg of ethinyl estradiol. The difference is that Loestrin Fe 1/20 has 21 active pills and 7 inactive pills, and Blisovi 24 Fe has 24 active pills and 4 inactive pills.
What are the alternatives to Loestrin Fe?
Answer:
There are a lot of different birth control options available that are similar to Loestrin Fe. Generic versions of Loestrin Fe 1/20 and Loestrin Fe 1.5/30 include Aurovela Fe, Blisovi Fe, Gildess Fe, Hailey Fe, Junel Fe, Microgestin Fe and Larin Fe.
Generic versions of the discontinued Loestrin 24 Fe include Larin 24 Fe, Aurovela 24 Fe, Gildess 24 Fe and Blisovi 24 Fe.
Is there an alternative to Lo Loestrin Fe?
Answer:
Lo Loestrin Fe is the lowest daily dose of estrogen currently available, so there’s nothing exactly like it. If you can take a slightly higher dose of estrogen, Loestrin Fe 1/20 is a possible alternative. Lo Loestrin Fe has 10mcg of estrogen in the active tablets and Loestrin Fe 1/20 has 20mcg.
There’s also a vaginal ring. NuvaRing has a slightly different hormonal makeup, containing etonogestrel instead of norethindrone acetate, but releases 15mcg of ethinyl estradiol every 24 hours.
What are the Loestrin Fe dosages?
Answer:
There are two types of Loestrin Fe, and the doctor will be able to further explain the differences and give you a tailored recommendation. Here are the basics, though.
Loestrin Fe 1/20 is a combined pill with a low estrogen content. It has 21 active tablets, which contain hormones, and 7 inactive ones, which contain iron. The active pills each have 1mg norethindrone acetate (a progestin) and 20mcg ethinyl estradiol (an estrogen). An mcg is a microgram, or 1/1000th of a milligram. It’s a really, really small amount.
Loestrin Fe 1.5/30 is the same thing but with slightly more of each active ingredient: 1.5mg of norethindrone acetate and 30mcg of ethinyl estradiol. You’ll take 21 pills with hormones and then 7 pills with an iron supplement.
Does Loestrin Fe cause weight gain?
Answer:
Studies haven’t shown a correlation between weight gain and the pill.[1] Some pills can cause water retention, which could show a fluctuation in weight. If your pill is causing you uncomfortable side effects, let a doctor know.
Nakajima, S.T., Archer, D.F. and Ellman, H. (2007). Efficacy and safety of a new 24-day oral contraceptive regimen of norethindrone acetate 1 mg/ethinyl estradiol 20 μg (Loestrin® 24 Fe). Contraception, 75(1), pp.16–22.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Why this page was updated on Jun 30, 2025
We reviewed the content on this page and made some structural changes to make it more reader-friendly and accessible.
Current version (Jun 30, 2025)
Edited by: The Treated Content Team.Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
Aug 01, 2022
Published by: The Treated Content Team.Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Cristina writes content for Treated, and reviews content produced by our other writers to make sure it’s clinically accurate.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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