Estarylla
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Reviewed on April 08, 2025. by
Dr. Joseph Palumbo
Senior Medical Adviser
Registered with NPI (No. 1043478878)
Next review due on
April 08, 2028.
Dr. Joseph Palumbo

Last updated on Sep 05, 2025.

The same active ingredients as Sprintec in a different pill.

Estarylla is a birth control pill you take every day and is 99% effective when taken correctly. It’s a combined oral contraceptive, so it contains two types of hormones: an estrogen and a progestin.

Price checker
0.25mg/0.035mg
$87.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $87.95
    Save $0.00 each order
Estarylla Norgestimate/Ethinyl Estradiol

What is Estarylla?

Estarylla (pronounced “es-tar-ill-ah”) is a combined hormonal birth control. It’s a pill you take every day at the same time. In combined birth control pills like Estarylla, you’ve got two hormones: an estrogen and a progestin. These trick your body into not doing the things it normally would to be pregnancy-ready.

Is Estarylla a combination pill?

Yes. Estarylla contains two hormones called norgestimate and ethinyl estradiol. These work in the body like natural hormones called progesterone and estrogen.

How does Estarylla work?

By altering the normal hormonal cycle your body goes through every month, they basically trick your ovaries into not releasing an egg. They also stop blood from settling on the uterine wall, so it’s harder for it to thicken and accept a fertilized egg for implantation. Something else they do is make cervical fluid thicker. This makes it more difficult for sperm to get through to an egg.

Estarylla and Tri-Estarylla: What’s the difference?

Estarylla and Tri-Estarylla are both birth control pills, but they deliver hormones differently. Estarylla is monophasic, meaning each active pill has the same hormone dose. Tri-Estarylla is triphasic, with hormone levels that change each week. Some people may prefer Tri-Estarylla if they experience side effects like breast tenderness or vaginal dryness from a continual hormone dose.

treated.com This page was written by The Treated Content Team.
Ms Laurenmarie Cormier
This page was medically reviewed by Ms Laurenmarie Cormier on April 08, 2025. Next review due on April 08, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Estarylla Norgestimate/Ethinyl Estradiol

How to take Estarylla

Estarylla comes in a 28-tablet pack, and it’s important to take your pill at the same time every day. You can start Estarylla either on the first day of your period (Day 1 start) or the first Sunday after your period.

With a Day 1 start, you’re protected against pregnancy right away, but with a Sunday start, you’ll need to use condoms for the first seven days.

treated.com This page was written by The Treated Content Team.
Ms Laurenmarie Cormier
This page was medically reviewed by Ms Laurenmarie Cormier on April 08, 2025. Next review due on April 08, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Estarylla Norgestimate/Ethinyl Estradiol

There are some things you need to watch out for when taking Estarylla, and not everyone can use it.

Here’s the official safety info. If there’s something you’re not sure about, let us know.

Estarylla Norgestimate/Ethinyl Estradiol

Estarylla: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Estarylla missed pill: What to do?

Answer:
If you miss one tablet in Weeks 1, 2, or 3, just take it as soon as you remember and continue taking one pill a day until the pack is finished.

If you miss two tablets in Week 1 or Week 2, take both missed tablets as soon as possible and then take the next two tablets the following day and use condoms for the next seven days if you have sex. Keep taking one pill a day after that.

If you miss two active tablets in Week 3, or miss three or more tablets in a row at any point, throw out the rest of the pack and start a new one right away and use back-up contraception for the next seven days.

How effective is Estarylla?

Answer:
When you take Estarylla right, it’s over 99% effective. This means that Estarylla pregnancy rates for women who take it perfectly are less than 1 in 100, over 12 months of use.

But forgetting a pill occasionally is pretty common. So for typical, “real-world” use, the effectiveness of combined pills like Estarylla is around 91%. So we’re talking 9 in 100 women getting pregnant over the course of a year.

Does Estarylla stop your period?

Answer:
When you take Estarylla, you’ll have a withdrawal bleed during your inactive pill week. So not quite the same as a period.

There is a way you can take Estarylla to stop bleeding altogether, which involves skipping the inactive pill week and going right onto your next pill pack. But you should check with the doctor before doing this, to make sure this method is right for you.

Are there many Estarylla generics?

Answer:
There are. Other brands of the Estarylla pill include Mono-Linyah, Ortho-Cyclen, MonoNessa, Previfem, Femynor, Sprintec, Mili and VyLibra.

These pills all contain the same hormones in the same amounts. So technically, they should work the same in the body. The main difference is that they’re made by different companies, so the prices are different. Sprintec and Previfem are a little cheaper than the others.

What are the most common side effects with Estarylla?

Answer:
Breast tenderness, nausea, headache and abdominal pain are listed as common side effects when starting Estarylla or similar pills.

Most medications carry a risk of side effects. With the pill, it’s typical for milder side effects to pass after a few weeks or months of use. Serious side effects are rare.[2] But if you continue to have these side effects or find them uncomfortable, let your doctor know.

Is Estarylla the same as Sprintec?

Answer:
If you’re talking hormones and dosage, yes, Estarylla is the same thing as Sprintec. But they’re made with different ingredients, by different companies and have different prices. Sprintec is a little cheaper than Estarylla.

So while they should work just the same, there are some small differences.

What if I want a lower dose of Estarylla?

Answer:
If you get mild side effects when taking Estarylla, Tri-Estarylla may be a better option. The level of progestin in this drug slowly increases over the three week active pill period. So it could be worth a switch if you get side effects like vaginal dryness or tender breasts.

There’s also a lower dose version of Tri-Estarylla, called Tri-Lo-Estarylla. This carries a slightly lower estrogen dose, and can be beneficial for women who get estrogenic side effects on higher doses.

Can you take Estarylla for acne?

Answer:
For some women, Estarylla might help with acne.[1] But there are other birth control pills that are indicated for acne and may do a better job. Let the doctor know during your consultation if you have acne problems and are seeking a pill that can help you with these symptoms.

Treated trusted source:

    1. Arowojolu, A, et al. 2012. Combined oral contraceptive pills for treatment of acne. U.S.A. Cochrane Library.
    2. Wright, K.P. and Johnson, J.V. (2008). Evaluation of extended and continuous use oral contraceptives. Therapeutics and Clinical Risk Management.

 

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Similar but different.

Combined pills: Here are your other options.

Apri
Apri Desogestrel/Ethinyl Estradiol

Pill with a "regular" estrogen dose. Very similar to Isibloom and Viorele.

0.15mg - 0.03mg
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Blisovi Fe
Blisovi Fe Norethindrone Acetate/Ethinyl Estradiol

There's an iron supplement in the inactive pills. A lot like Loestrin Fe and Junel Fe.

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Junel Fe
Junel Fe Norethindrone Acetate/Ethinyl Estradiol

The inactive pills contain an iron supplement. Similar to Loestrin Fe and Blisovi Fe.

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Portia
Portia Levonorgestrel/Ethinyl Estradiol

A daily combined pill that helps prevent pregnancy. May make your period lighter and less painful.

0.15mg - 0.03mg
$129.95
$129.95
See this option
Sprintec
Sprintec Norgestimate/Ethinyl Estradiol

Daily birth control that can help manage irregular periods and acne. Similar to Estarylla and Femynor.

0.25mg - 0.035mg
$84.95
$84.95
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Vienva
Vienva Levonorgestrel and Ethinyl Estradiol

Daily birth control pill. A low-dose pill, so you’re less likely to get side effects.

0.1mg/0.02 mg
$81.95
$81.95
See this option
Yasmin blister
Yasmin Drospirenone/Ethinyl Estradiol

The same active ingredients as Yaz but with a little more estrogen.

$309.95
$309.95
See this option
Yaz
Yaz Drospirenone/Ethinyl Estradiol

Birth control that helps manage acne. Low-dose version of Yasmin.

0.02mg - 3mg
$257.95
$257.95
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