Oracea ®
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Reviewed on September 18, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on
September 18, 2028.
Dr Alexandra Cristina Cowell

Last updated on Nov 07, 2025.

Antibiotic capsule for folliculitis.

Oracea is a capsule treatment for rosea, which can be used ‘off-label’ to manage folliculitis. It contains doxycycline, a type of antibiotic known as a tetracycline.

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40mg
$1,734.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
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Oracea Doxycycline

What is Oracea?

Oracea is a branded form of doxycycline, a type of tetracycline antibiotic. It can help to heal sore, itchy, and inflamed hair follicles caused by folliculitis.

The capsules contain a ‘non-antibiotic’ dose, which means that unlike higher doses of the same active ingredient that work as antibiotics, they can be used long-term to manage inflamed hair follicles.

Who is Oracea for?

Oracea is usually prescribed for adults with rosacea, but it can also be prescribed ‘off-label’ for folliculitis.

Folliculitis often occurs as a result of hair follicles becoming inflamed— this can happen as a result of viral and bacterial infections, but also as a result of inflammation or blocked pores. Bacterial infections are the most common cause of folliculitis.[1]

Why is Oracea prescribed ‘off-label’?

Off-label prescribing is when medications are used outside of their stated license. It’s a common practice, and done if a prescriber thinks using a medication this way will work effectively.

Oracea would typically be used when folliculitis symptoms are severe.[2]

How does Oracea work?

Tetracycline antibiotics like Oracea work by reducing inflammation.

Your physician might prescribe Oracea to help reduce soreness and inflammation, which can help unclog infected follicles and allow the surrounding skin to heal.

Does Oracea come in different doses?

Oracea comes as a single dose, 40mg capsule.

The capsules contain 30mg doxycycline which hits your stomach soon after you’ve taken it, and another 10mg is released when the medication reaches your small intestine a few hours later. This low-dose formula means you can take Oracea for longer than you typically would with the usual 100mg doses of doxycycline.

Treated trusted source:

  1. Winters, R.D. and Mitchell, M. (2023). Folliculitis.
  2. FDA (2018). Understanding Unapproved Use of Approved Drugs ‘Off Label’. U.S. Food and Drug Administration.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on September 18, 2025. Next review due on September 18, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Oracea Doxycycline

How to take Oracea

You should take Oracea exactly how it’s been prescribed to you by your doctor.

The usual dose is one capsule, taken in the morning. Oracea needs to be taken on an empty stomach, around one hour before or two hours after a meal.

Swallow the capsules whole with a glass of water.

If for any reason you miss a dose, skip the missed dose and continue with your usual dosage routine rather than taking more than one capsule to make up for it.

How long does Oracea take to work?

Oracea will start to work in your system soon after you’ve taken your first capsule, but it might take a bit longer than this before you start to see the effects of the medication.

Studies have shown that Oracea can improve your skin in as little as three weeks, but is most effective after 16 weeks.[1]

Treated trusted source:

  1. Oracea.com. (2020). The efficacy of ORACEA® (doxycycline, USP) 40 mg Capsules.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on September 18, 2025. Next review due on September 18, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Oracea Doxycycline

Oracea isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

 

Oracea Doxycycline

Oracea: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How effective is Oracea?

Answer:
Studies have shown that doxycycline is an effective treatment for managing severe forms of folliculitis, such as eosinophilic pustular folliculitis,[1] which involves itching, redness and pustules.[2]

Although there aren’t a lot of studies about Oracea treating folliculitis specifically, taking a 40mg daily dose of doxycycline has been shown to improve skin inflammation and lesions caused by rosacea, when used for 16 weeks.[3]

How is Oracea different from other treatments for folliculitis?

Answer:
Doxycycyline is one type of oral antibiotic that can be used for managing folliculitis, others include flucloxacillin, cephalexin and clindamycin. Antibiotics are typically prescribed if it seems like a bacterial infection is causing your folliculitis symptoms.

As well as oral antibiotics, topically applied antibiotics like mupirocin and fusidic acid are used. These are usually available as creams and gels, and can be applied several times a day depending which one you use.

Oracea is different from other antibiotics because it works at a lower, ‘non-antibiotic’ dose, which means it can be used for longer than typical short courses of antibiotics.

 

Can I drink alcohol while using Oracea?

Answer:
Although Oracea contains a lower dose of antibiotic than most courses that are prescribed for managing bacterial infections, it’s still advised you limit or avoid alcohol altogether while taking it.

Alcohol can reduce the effectiveness of doxycycline, so drinking it could potentially prevent the capsules from working properly and slow the healing of your skin.

Will Oracea cause side effects?

Answer:
Some common side effects Oracea can cause include nasopharyngitis, which is swelling of the nasal passages, diarrhea, and hypertension.

As with all medications, there is a chance you’ll experience side effects, but this doesn’t mean they’re guaranteed. If you experience any uncomfortable side effects that are difficult to manage or don’t settle, let your physician know. They can recommend some alternative treatment options that might be better suited to you.

Do I need a prescription for Oracea?

Answer:
You’ll need a prescription to start using Oracea. This is so your physician can check it’s the best, most suitable treatment option for managing your folliculitis

As well as the capsules, you might be advised to try some home remedies that can help relieve folliculitis symptoms, such as applying a warm compress to any affected areas.

 

Is Oracea available through private health insurance?

Answer:
Not all types of treatments are covered by health insurance, so you’d need to check what is included in your plan.

Folliculitis can affect people differently, so the severity of your symptoms might dictate whether your medication is covered by insurance — if it’s deemed to be a medical necessity, then it usually will be included. If it isn’t, you’ll have to cover the costs and get Oracea privately.

Treated trusted source:

  1. Ono, S., et al (2013). Evaluation of the Effectiveness of Antibiotics against Eosinophilic Pustular Folliculitis. Case Reports in Dermatology, 5(2), pp.144–147.
  2. Dermnetnz.org. (n.d.). Eosinophilic folliculitis | DermNet NZ.
  3. Del Rosso, J.Q., et al (2007). Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for treatment of rosacea. Journal of the American Academy of Dermatology, 56(5), pp.791–802.

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