Onexton

What is Onexton?

Onexton is a topical prescription gel that contains clindamycin phosphate, an antibiotic, and benzoyl peroxide, a keratolytic and antibacterial agent. It belongs to a class of medications known as combination topical antimicrobials.

Onexton is primarily prescribed for acne, but doctors can prescribe it ‘off-label’ for other skin conditions like bacterial folliculitis, where clogged follicles and bacterial overgrowth cause inflammation and pustules. ‘Off-label’ simply means it’s being used for a condition not mentioned in the leaflet. It’s a common practice among doctors, and they only do it when there’s evidence to show it’ll be safe and effective for you.

How does Onexton work for folliculitis?

Onexton works in two ways:

• Clindamycin phosphate works by blocking the synthesis of proteins that bacteria need to grow. It’s particularly effective at slowing the growth of Staphylococcus aureus, a common cause of folliculitis.^[1]
• Benzoyl peroxide helps to unclog pores by reducing oil and dead skin buildup, and lowers inflammation. It also kills acne-symptom causing bacteria by releasing oxygen free radicals.^[2]

Will I get side effects using Onexton?

You can experience side effects using Onexton, but not everyone gets them. Some common ones include: 

• mild redness, 
• dryness, 
• peeling, 
• or burning at the application site. 

Onexton can also cause your skin to be more sensitive to sun, so you should make sure to wear sunscreen during treatment.

If you experience any kind of allergic reaction – itching, rash, or swelling – stop using Onexton and get medical help.

What doses of Onexton are there?

Onexton comes as a gel in a single strength: clindamycin phosphate 1.2% and benzoyl peroxide 3.75%. You’ll usually apply it once a day in a thin layer to affected areas. 

How to use Onexton

Apply Onexton once a day. To use it:

• Wash your skin gently with a mild cleanser and pat dry before applying.
• Apply a thin layer of gel once a day to the affected area.
• Avoid your eyes, mouth, and any broken skin.
• Wash your hands after applying Onexton.

You should apply Onexton before applying your moisturizer.

What should I do if I use too much Onexton?

If you apply too much Onexton, just wash off the excess with water. Using extra Onexton won’t make it work faster and could cause more irritation, redness, and peeling.

If you accidentally swallow any gel, contact your doctor or seek medical advice straight away.