Zithromax is an oral antibiotic used to treat chlamydia. It comes in the form of a 1g tablet that you take once a day for three days.
The generic name for Zithromax is azithoromycin, which is the active ingredient of zithromax. Zithromax is usually prescribed when the first-line treatment for chlamydia, doxycycline, isn’t suitable.
Chlamydia is the highest reported bacterial disease in the US.[1] It’s very common and easily treatable. You might not even know you have it initially, as it often doesn’t come with symptoms. Symptoms you might notice are:
Unusual discharge from the penis or vagina
Pain when urinating
In men, you might notice swollen and painful testicles
In women, you might notice pain in your tummy, and ‘spotting’ (bleeding) after sex and in between your periods.
It’s important to get regular sexual health check-ups. If chlamydia goes untreated, it can spread and cause infections in other parts of your body which can cause long-term health problems.
Before you can get treatment for your chlamydia, you’ll need to provide a positive test result. Pop into a sexual health clinic and grab a test before your consultation. If your partner receives a positive test result, there’s a chance you could be prescribed antibiotics before your own test results are confirmed.
When your treatment course has ended, it’s a good idea to take another test about three weeks later to make sure your treatment has worked.
How does Zithromax work?
Zithromax contains the active ingredient azithromycin. Azithromycin works by stopping the growth of the chlamydia bacteria in your cells. It doesn’t hurt the bacteria directly, but it blocks their ability to make proteins in the cells they infect.[2]
After treatment, you should wait at least a full week before having sex again, including oral sex.
Treated trusted source:
ACOG (2025). Chlamydia, Gonorrhea and Syphilis. FAQs. [online] The American College of Obstetricians and Gynaecologists.
Engel, J.N. (1992).Azithromycin-induced block of elementary body formation in Chlamydia trachomatis. Antimicrobial Agents and Chemotherapy, 36(10), pp.2304–2309.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on January 30, 2024. Next review due on January 30, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
ZithromaxAzithromycin
How to take Zithromax
If you’re taking Zithromax for chlamydia then you’ll normally be prescribed a 1g dose set of pills, in either four doses of 250mg, or two doses of 500mg.
Always swallow your pills whole, don’t crush them or chew them.
Take your pills as directed. This will normally be one a day for two or four days. You can take it in the morning or at night, and with or without food.
Always take the full course of pills, even if you start to feel better.
Can I take Zithromax when pregnant or breastfeeding?
Azithromycin is generally considered safe during pregnancy if you’ve got an infection that requires treatment.
It’s important to let your doctor know if you’re pregnant or trying, as they can discuss the associated risks and benefits with you.
If your baby has been confirmed to be healthy by your doctor, it should be fine to take azithromycin while breastfeeding. The antibiotic passes into breast milk in small amounts, and there have been no reported side effects in breastfed babies.
Are there different forms of Zithromax?
At Treated, we only have Zithromax in a pill form, but you can also get Zithromax that comes in the form of a liquid. This will usually be made up by your pharmacist for you.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on January 30, 2024. Next review due on January 30, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
ZithromaxAzithromycin
Zithromax isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
ZithromaxAzithromycin
Zithromax: FAQ
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
What alternatives are there to Zithromax?
Answer:
When it comes to treating chlamydia, antibiotics are the suggested and prescribed treatment.[1]
Zithromax (azithromycin) is one antibiotic option. The other most commonly prescribed treatment is the antibiotic doxycycline. This is normally taken over a seven day period, a more extended duration than the three day course for zithromax.
There are other antibiotics you can try too, like tetracycline, erythromycin, or ofloxacin.
You and your doctor will decide what the best treatment will be for you depending on what you need.
Are there any side effects from Zithromax?
Answer:
Like all medicines, Zithromax can cause side effects, though not everybody will get them.
The most common side effects that people experience are:
Nausea and vomiting
Headaches
Feeling tired or dizzy
Losing appetite
Diarrhea
Changes to your sense of taste
You can drink alcohol while on Zithromax; but if you find that Zithromax makes you dizzy it’s best to avoid it, as alcohol will make your dizziness worse.
You may experience all or none of these side effects, and if you do, they’ll most likely go away once you’ve finished your course of treatment. If these side effects are causing you any issues, get in touch with your physician and let them know.
How well does Zithromax work for chlamydia?
Answer:
Zithromax is a proven effective treatment for chlamydia. In a study, researchers compared a single 1g dose of azithromycin - the active ingredient in Zithromax - with the standard 7-day course of doxycycline for chlamydia treatment in sexually active young people.
The results showed that azithromycin had an 8.7% treatment failure rate, which was similar to the 14.8% result in the group who were treated with doxycycline.
The study found that 97.4% of azithromycin-treated patients showed improvement and reduction of their symptoms after 4 weeks.[1]This suggests Zithromax is a safe and effective treatment for chlamydia, comparable to doxycycline.
Can you get Zithromax over the counter?
Answer:
You can only get antibiotics with a prescription – to make sure they are used the right way. A clinician needs to ask you questions and make sure they’re the treatment that’s best for you.
This helps prevent problems like using antibiotics too much or in the wrong way, which can make them less effective over time and cause antibiotic resistance.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Jan 29, 2024
Published by: The Treated Content Team.Medically reviewed by: Dr. Joseph Palumbo, Senior Medical Adviser
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Dr. Joseph Palumbo
Senior Medical Adviser
Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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