Uloric
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Reviewed on May 02, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on
May 02, 2028.
Dr Alexandra Cristina Cowell

Last updated on May 01, 2025.

Stops uric acid production.

Uloric is an oral treatment that stops the production of uric acid, helping relieve joint pain and inflammation. 

Price checker
$299.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $299.95
    Save $0.00 each order
Uloric Febuxostat

What is Uloric?

Uloric is a treatment for gout, a condition that’s characterised by the buildup of uric acid crystals around the joints, causing pain and discomfort.

It’s available as a tablet and is typically taken once a day.

How does Uloric work?

Gout is caused by the buildup of uric acid crystals in the joints

Febuxostat, the active ingredient in Uloric, works by inhibiting the enzyme that makes uric acid, helping stop production. It may also help dissolve existing crystals, which further reduces swelling.[1]

Will I get side effects using Uloric?

Like any medicine, Uloric can cause side effects for some people. That doesn’t mean you’ll get any, though – many people don’t. Here are some of the most common ones:

  • Diarrhea
  • Headache
  • Rash
  • Nausea
  • Swelling

For the full list of side effects, check the package insert that comes with your medication.

Some people may also experience an increase in gout attacks. This usually occurs when existing crystals dissolve.

Is there a generic version of Uloric?

Uloric is a branded version of the generic treatment (simply called Febuxostat, the name of the active ingredient). They contain the same active ingredient in the same concentration, so should be equally effective.

The main differences lie in the packaging and price – generic medications tend to be cheaper than their branded equivalents.

What doses of Uloric are there?

Uloric is available in two doses: 40 mg and 80 mg.

While the dosage can vary depending on the severity of your symptoms, it’s usually 40mg at the start of treatment, which can be raised to 80mg daily. For severe cases, the dose can be increased to a maximum of 120mg.

Treated trusted source:

  1. Gerriets V, Patel P, Jialal I. Febuxostat. [Updated 2024 May 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on May 02, 2025. Next review due on May 02, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Uloric Febuxostat

How to take Uloric

Swallow one tablet whole with water, with or without food. Try to take it around the same time each day, preferably in the morning.

You should continue taking Uloric even if you’re not experiencing gout flares. Stopping treatment can increase the risk of side effects and gout attacks.

Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on May 02, 2025. Next review due on May 02, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Uloric Febuxostat

Uloric isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Uloric Febuxostat

Uloric: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Can I get Uloric through private health insurance?

Answer:
Most private healthcare plans in the USA will cover gout treatments, but there may be some that only cover specific medications. So if you’re looking to get Uloric and have private health insurance, you should check your plan to make sure it’s covered.

If Uloric isn’t covered, your insurance may cover a similar or generic version. If not, you can always get treatment directly from an online prescription and pharmacy service.

Will Uloric cause my gout symptoms to worsen?

Answer:
Yes, your symptoms can temporarily worsen while taking Uloric. Uloric works by preventing the formation of new uric acid crystals, and in the process, it may also cause existing crystals to dissolve. This can increase the level of uric acid in your bloodstream, which may trigger gout attacks. This will, however, be beneficial for your long-term health.

It can take several months or years for existing crystals to dissolve completely. Your doctor may recommend taking anti-inflammatory medication alongside Uloric to help manage your gout attacks.[1]

How does Uloric compare with Allopurinol?

Answer:
Uloric acid and Allopurinol are two treatments for Gout. They both belong to a class of drugs called xanthine oxidase inhibitors, which work by preventing uric acid formation.

There isn't much difference between the two. The one you choose really depends on your personal preference and medical history, as Uloric carries an increased risk of heart-related problems.

How long does Uloric take to work?

Answer:
Uloric is rapidly absorbed (approximately within two hours of taking it). But it can take several months of consistent use before you notice an improvement in symptoms.[2]

Some people might get more gout attacks in the first few months. To help with this, your doctor will recommend taking a non-steroidal anti-inflammatory drug like Advil.

Will Uloric raise my blood pressure levels?

Answer:
It’s unlikely that Uloric will increase your blood pressure. Some studies have found it actually decreases blood pressure, particularly in people with hypertension and high uric acid levels.[3]

Your doctor will check your medical history before prescribing it to check that it's safe for you. You might also need to regularly monitor your blood pressure levels during the treatment.

When is the best time to take Uloric?

Answer:
You can take Uloric at any time during the day, but it is best to take it in the morning to manage your symptoms throughout the day.

Can I take Uloric during a gout attack?

Answer:
Your doctor may advise you to wait until your gout attack has passed before prescribing the medication. This is because taking it mid-attack may worsen the pain and inflammation.

How do I stop taking Uloric?

Answer:
Let your doctor know if you want to stop taking Uloric. They’ll advise how to do so safely and effectively.

Don't stop taking Uloric without medical supervision, as this may lead to unwanted side effects.

Treated trusted source:

  1. Gerriets V, Patel P, Jialal I. Febuxostat. [Updated 2024 May 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.
  2. EMC (2022). Febuxostat 120 mg Film-coated Tablets – Summary of Product Characteristics (SmPC) – (emc) | 13756.
  3. Yao, J., et al. (2020). Effect of febuxostat on blood pressure in hyperuricemic patients: A protocol for a systematic review and meta-analysis. Medicine, 99(24), e20673.

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