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Last updated on Jan 02, 2025.
Metoclopramide is a nausea treatment that works by blocking signals in the brain.
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Metoclopramide is a medication used to treat nausea. It can help your symptoms by stopping you from feeling and being sick.
It’s a generic version of the branded medicines Metozolv and Reglan. This means they both contain the same active ingredient and work in about the same way but Metoclopramide is usually cheaper.
Metoclopramide is a short course of treatment and you should take it for a maximum of five days.
Nausea is the feeling of needing to be sick, which sometimes triggers actual vomiting. It’s often triggered when nerves in a part of your body are irritated and send signals to a part of your brain called the CTZ (chemoreceptor trigger zone). The CTZ then sends signals via dopamine to the vomiting centre.
The vomiting centre can cause spasms in the gut and feelings of sickness. Metoclopramide works by interrupting the messages that are sent between the CTZ and the vomiting centre. This should reduce nausea and curb the risk of vomiting.
The standard dose of Metoclopramide is 10mg, taken up to three times a day. If this isn’t effective enough at reducing nausea, your doctor might recommend a higher dose of up to 30mg.
If you suffer from a liver or kidney condition, or if you weigh less than 132 lbs, a standard dose of Metoclopramide could be too high for you. In this case, you will need to talk to our doctor about a lower dose.

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Always take the dosage of Metoclopramide prescribed by our doctor. Swallow it with water. Wait at least six hours between each dose, even if you’ve been sick.
You’ll usually start to feel better half an hour to an hour after taking Metoclopramide.
Metoclopramide is usually prescribed for up to five days. This can vary depending on why you’re using it.
If you’re taking it for migraines, you should only take it as and when your symptoms appear. If you’re taking it for nausea caused by chemotherapy or surgery, take for as long as it has been prescribed.
Maybe you feel like you need more nausea treatment after finishing your course, or you’re not sure how much you were supposed to take. In this case, go back and talk to our doctor. You just need to sign in to your account and send our clinician a message.
If you’ve taken more Metoclopramide than you should, contact a clinician or go to your local hospital. Bring the packaging of the medication with you if possible.
If you miss a dose, don’t take a double dose to make up for it. Just skip a dose and continue treatment as normal.

How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Metoclopramide isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
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Last updated on Jan 2, 2025.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Jan 02, 2025
Published by: The Treated Content Team. Medically reviewed by: Dr. Joseph Palumbo, Senior Medical AdviserHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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