Levofloxacin
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Reviewed on November 11, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on
November 11, 2028.
Dr Alexandra Cristina Cowell

Last updated on Nov 12, 2025.

Can treat sinusitis in under a week.

Levofloxacin is an oral antibiotic that’s available in two doses. It’s taken daily and can treat bacterial sinusitis.

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Levofloxacin Levofloxacin

What is Levofloxacin?

Levofloxacin is an oral antibiotic that treats bacterial sinusitis, an infection that causes inflammation in the sinuses. This leads to symptoms like blocked and stuffy nose. While you don’t always need treatment for sinusitis, Levofloxacin can speed up your recovery.

How does Levofloxacin work?

Levofloxacin is an antibiotic that stops bacterial growth. It does this by inhibiting the production of bacterial DNA. Without DNA, the bacteria can’t grow or replicate.[1]

Will I get side effects from Levofloxacin?

Like all medicines, there is a risk of getting side effects, although not everyone will experience them. The most common ones include:

  • Sleeping problems
  • Headache
  • Feeling dizzy
  • Nausea
  • Vomiting
  • Diarrhea

These side effects should only last a short while and subside when you stop your medication. For a full list of side effects, check the package leaflet that comes with your medication.

Can I drink alcohol with Levofloxacin?

While there’s no interaction between alcohol and Levofloxacin, it’s best to avoid it while on treatment. This is because it can increase the risk of side effects like dizziness and nausea.

What doses of Levofloxacin are there?

Levofloxacin comes in two doses: 500 mg and 750 mg. The usual dose is one tablet a day for up to two weeks, depending on the dose

Treated trusted source:

  1. Podder, V. and Sadiq, N.M. (2024). Levofloxacin. www.ncbi.nlm.nih.gov. StatPearls Publishing.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 11, 2025. Next review due on November 11, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Levofloxacin Levofloxacin

How to take Levofloxacin

Swallow the tablet whole with water. It’s best to take it with a meal or after a meal. You don’t have to take it with food, but taking it with food can reduce your risk of side effects and help it work more effectively.

Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 11, 2025. Next review due on November 11, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Levofloxacin Levofloxacin

Levofloxacin isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Levofloxacin Levofloxacin

Levofloxacin: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Can I get Levofloxacin through private health insurance?

Answer:
Levofloxacin may be available through your private health insurance, but it's best to check with your provider if they actually cover it. Some providers only cover certain brands or antibiotics.

If they don't cover it, you can still get Levofloxacin with Treated, but you will have to pay out of pocket, and it’s unlikely it will be reimbursed.

How long does Levofloxacin take to work?

Answer:
Levofloxacin gets to work quickly, but it may take a few days to notice an improvement in your symptoms. When you do feel better, don't stop taking it. Leaving your treatment unfinished can cause your infection to return (and potentially make it harder to fight back).

Can I take Levofloxacin with Ibuprofen?

Answer:
You can take Levofloxacin with Ibuprofen, but taking both together might cause side effects. If you have to take them both, take them at different times. For more information, message your doctor.

How does Levofloxacin compare with other treatments for sinusitis?

Answer:
Levofloxacin isn't the first choice of treatment for bacterial sinusitis; it’s usually prescribed if amoxicillin hasn't worked well for you or you can't take it for whatever reason.

Other treatments include different types of antibiotics, corticosteroids, which help reduce inflammation, and nasal sprays to relieve symptoms.

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