Ketoconazole
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Reviewed on November 21, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on
November 21, 2028.
Dr Alexandra Cristina Cowell

Last updated on Dec 04, 2025.

Effective anti-fungal cream for paronychia.

Ketoconazole is an antifungal cream that helps treat fungal paronychia. It’s applied twice a day for up to six weeks.

Price checker
2% cream
$74.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $74.95
    Save $0.00 each order
Ketoconazole Ketoconazole

What is Ketoconazole?

Ketoconazole is an antifungal cream that helps treat fungal paronychia, a condition characterized by redness, tenderness, and swelling around the nail fold. In some cases, the nail can also appear discoloured, develop ridges, or even separate from the nail bed.

Paronychia can be caused by both bacterial and fungal infections, so your doctor will assess your symptoms to prescribe the most suitable treatment for you.

How does Ketoconazole work?

Ketoconazole is an antifungal that works by stopping the growth of ergosterol – the primary component in the fungal cell wall. Without it, the cell wall becomes more permeable, which prevents growth and eventually clears the fungal infection.[1]

Will I get side effects using Ketoconazole?

Like all medicines, there’s a risk of getting side effects when using Ketoconazole, but not everyone will experience them. Common side effects include itching and a burning sensation on the treated area, but in many cases these only last a short while. For the full list of side effects, check the package leaflet that comes with your medicine.

How long does Ketoconazole take to work?

Ketoconazole begins to work quickly, but it can take a few days before you notice visible improvements in your symptoms. If you have chronic paronychia, which is typically caused by fungus, it might take a few weeks for it to completely heal.[2] Additionally, if the infection has affected your nail, it will take a few months for the affected portion of nail to grow out and return to normal.

What doses of Ketoconazole are there?

Ketoconazole comes in a single dose of 2%. You typically apply it twice a day for up to six weeks.

Treated trusted source:

  1. Sinawe H, Casadesus D. (2023). Ketoconazole. StatPearls. Treasure Island (FL): StatPearls Publishing.
  2. Publishing, H.H. (n.d.). Paronychia. [online] Harvard Health.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 21, 2025. Next review due on November 21, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Ketoconazole Ketoconazole

How to use Ketoconazole

To use Ketoconazole:

  1. Wash and dry the affected area. 
  2. Apply a thin layer of cream to the affected and surrounding area.
  3. Wash your hands after applying it.
  4. Repeat twice a day. 

Avoid sharing your towel or clothing with other people to help prevent the spread of infection.

Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 21, 2025. Next review due on November 21, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Ketoconazole Ketoconazole

Ketoconazole isn’t suitable for everyone, and there are some things that you need to be aware of when using it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Ketoconazole Ketoconazole

Ketoconazole: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How can I avoid reinfection after stopping Ketoconazole?

Answer:
Fungal paronychia is a slow-developing infection that often becomes chronic. As a result, it requires multiple weeks or months of treatment to clear the infection. You should use Ketoconazole consistently, even if you think your symptoms improve, as the infection could still linger without any signs.

After the infection is treated, you can take steps to prevent reinfection. For example, avoid prolonged exposure to water and keep the affected areas dry. Also, avoid wearing gloves or socks, as these can create a moist environment where the fungus can thrive.

How does Ketoconazole compare with other treatments for paronychia?

Answer:
There are several treatments for paronychia, which can include both antibiotics and antifungal medications in oral and topical forms. The specific treatment you receive will depend on the cause of the infection – whether it’s bacterial or fungal.

Your doctor will check your symptoms and prescribe the appropriate antimicrobial for your condition. If the infection is severe or persistent, they might recommend oral medications, as these tend to be more effective than topical treatments because they work systemically.[1]

Can I use Ketoconazole while pregnant?

Answer:
You can use Ketoconazole while pregnant and breastfeeding, but inform your doctor or midwife before using it.

If you’re breastfeeding, wash your hands after applying the cream and avoid applying it to your breast to prevent it from affecting your baby.

Can I get Ketoconazole through private health insurance?

Answer:
You might be able to get Ketoconazole with your private insurance, but it's best to contact them to check if they cover it.

If they don't, you can get Ketoconazole from a private prescription service, but you’ll have to pay for this yourself and you may not be eligible for reimbursement.

Treated trusted source:

  1. Sinawe H, Casadesus D. (2023). Ketoconazole. StatPearls. Treasure Island (FL): StatPearls Publishing.

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