Famotidine
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Reviewed on April 07, 2025. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Next review due on
April 07, 2028.
Dr Alexandra Cristina Cowell

Last updated on Apr 06, 2025.

Product info

  • Famotidine is an antihistamine that helps relieve allergy symptoms.

  • It can’t treat anaphylaxis, but it helps alleviate symptoms caused by it.
  • It’s available in three doses: 10 mg, 20 mg and 40 mg.

Price checker
$89.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $89.95
    Save $0.00 each order
Famotidine Famotidine

What is Famotidine?

Famotidine is an antihistamine that helps relieve symptoms of allergic reactions. Although it can’t treat anaphylaxis, which requires immediate treatment with epinephrine, it can help prevent late-phase reactions and relieve gastrointestinal (GI) symptoms.

Anaphylaxis is a potentially life-threatening condition that, like any allergy, is usually triggered by your immune system overreacting to an otherwise harmless substance. It’s treated with epinephrine, which works within seconds to alleviate symptoms, as well as help from trained medical professionals.

How does Famotidine work?

Famotidine is an H2-antihistamine that blocks H2 receptors by binding to them. Histamine is a key chemical involved in anaphylaxis. It widens the blood vessels, causing the blood pressure to drop, and narrows the smooth muscles in your airways, making it hard to breathe.[1]

By blocking the receptors, Famotidine helps alleviate symptoms. Although it’s not a first-line treatment, it can prevent late-phase reactions or treat GI symptoms caused by anaphylaxis.

Famotidine may be used alongside an H1-antihistamine to make it more effective.[2]

What doses of Famotidine are there?

Famotidine is available in three doses: 10 mg, 20 mg and 40mg tablets. The typical dose is up to 40 mg a day for two to three days after the anaphylactic reaction. Your doctor will tell you exactly how much Famotidine to take when they prescribe it to you.

Treated trusted source:

  1. Nguyen K, Dersnah GD, Patel P, et al. Famotidine. [Updated 2024 Jan 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
  2. Mustafa, S. (n.d.). Anaphylaxis Medication: Adrenergic Agonists, Antihistamines, H2 Receptor Antagonists, Bronchodilators, Corticosteroids, Positive Inotropic Agents, Vasopressors. [online] emedicine.medscape.com.
treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on April 07, 2025. Next review due on April 07, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Famotidine Famotidine

How to take Famotidine

Swallow one tablet whole with water 15 minutes to one hour before eating. If you’re taking multiple tablets daily, space them out evenly throughout the day.

How long does Famotidine take to work?

Famotidine is quickly absorbed, reaching peak concentration within one to three hours, and its effects can last approximately 10 to 12 hours.

I made a mistake when taking Famotidine, now what?

If you forget to take a dose, take it as soon as you remember, unless it’s close to the next scheduled dose. In that case, skip the missed dose and continue with your dosing schedule.

If you took more than the recommended dose, contact your local emergency department immediately. You may experience symptoms like a headache or dizziness.

treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on April 07, 2025. Next review due on April 07, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Famotidine Famotidine

Famotidine isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Famotidine Famotidine

Famotidine: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

What is Famotidine used for?

Answer:
Famotidine is commonly used to treat gastroesophageal reflux disease (GERD), a condition where stomach acid rises to the throat, causing heartburn and digestive issues. Famotidine stops acid production by blocking the H2 receptors in the stomach, helping treat GERD.

It can also help treat other conditions like stomach ulcers, acid indigestion, and Zollinger-Ellison syndrome.

It’s not a primary treatment for anaphylaxis, which is typically treated with epinephrine, but it can relieve GI symptoms caused by anaphylaxis and prevent late-phase anaphylaxis symptoms.

Will I get side effects using Famotidine?

Answer:
There’s a chance of experiencing side effects when using Famotidine, including:

  • Headache

  • Dizziness

  • Constipation

  • Diarrhea

  • Loss of appetite


For the full list of side effects, check the package insert.

The side effects should subside when you stop using Famotidine. But if they persist or worsen, contact your doctor for medical advice.

Is there a branded version of Famotidine?

Answer:
Famotidine is a generic version of Pepcid and Zantac. They contain the same active ingredient and work similarly, so they should be just as effective as each other. Aside from that, there are a few differences, such as the packaging, formula, concentration and price, with the generic version usually being cheaper.

Can I take Famotidine during pregnancy?

Answer:
No, you should avoid taking Famotidine during pregnancy. While specific info is limited, some studies suggest it may reach your unborn baby. Likewise, Famotidine should be avoided when breastfeeding as it can pass into breastmilk.

Your doctor will only prescribe Famotidine if they believe that its benefits will outweigh the risks.

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