Bonine
We’ll deliver to you in 2-5 days
Price checker
25mg
$399.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $399.95
    Save $0.00 each order
Reviewed on March 20, 2025. by
Dr. Joseph Palumbo
Senior Medical Adviser
Registered with NPI (No. 1043478878)
Next review due on
March 20, 2028.
Dr. Joseph Palumbo

Last updated on Mar 19, 2025.

Product info

  • Bonine is a motion sickness tablet that can provide 24-hour relief.

  • It’s taken one hour before starting your journey.
  • Bonine is the branded version of meclizine.

Price checker
25mg
$399.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    $399.95
    Save $0.00 each order
Bonine Meclizine

What is Bonine?

Bonine is a motion sickness tablet that can provide 24-hour relief. It contains meclizine, a first-generation antihistamine that has anti-nausea and anti-vertigo effects.[1] This helps prevent and relieve motion sickness when traveling by car, boat or plane.

Motion sickness is triggered by conflicting signals between your eyes and ears. This confuses your brain, leading to dizziness and nausea. Taking Bonine an hour before your journey can help alleviate motion sickness, making your journey more comfortable.

How does Bonine work?

Meclizine, the active ingredient in Bonine, is a first-generation antihistamine that also has anticholinergic actions. Histamine and acetylcholine are neurotransmitters that play a significant role in motion sickness, with high levels being associated with nausea and dizziness.

Meclizine helps relieve motion sickness symptoms by blocking histamine and acetylcholine receptors.[1]

What doses of Bonine are there?

Bonine is available in two doses: 25 mg and 50 mg. While the first dose is available under the name Bonine, the higher dose is sold under Bonine Max The usual dose is one 25 mg tablet once a day. You can take up to a maximum of 50 mg once a day. Your doctor will recommend which dose you should use.

Treated trusted source:

  1. Houston BT, Patel P, Chowdhury YS. Meclizine. [Updated 2024 Feb 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
treated.com This page was written by The Treated Content Team.
Dr. Joseph Palumbo
This page was medically reviewed by Dr. Joseph Palumbo on March 20, 2025. Next review due on March 20, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Bonine Meclizine

How to take Bonine

To take Bonine:

  • Crush or chew the tablet completely when taking it. 
  • Take it an hour before traveling to give it enough time to start working. 
  • Don’t swallow the tablet whole as this can delay its effects.

As Bonine can cause drowsiness, you should avoid driving or operating machinery. 

How long does Bonine take to work?

Bonine begins to work within one hour and can provide relief for up to 24 hours when taken correctly. Meclizine has a half-life of five to six hours, so the effects may decrease after this time and should wear off completely by 24 hours.

treated.com This page was written by The Treated Content Team.
Dr. Joseph Palumbo
This page was medically reviewed by Dr. Joseph Palumbo on March 20, 2025. Next review due on March 20, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Bonine Meclizine

Bonine isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.

Bonine Meclizine

Bonine: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Is Bonine similar to any other medicine?

Answer:
Bonine is the branded version of the generic medicine called Meclizine. Both contain the same active ingredient, so you shouldn't notice any difference in effectiveness between the two. But there are a few key differences.

  • Dosage: Bonine comes as a 25 mg or 50 mg tablet, while generic Meclizine comes in 12.5 mg and 25 mg tablets.

  • Price: Generic medications tend to be cheaper than the branded versions.

  • Non-active ingredients: The ‘excipient (non-active) ingredients, like the coating of the tablets, may differ, but this shouldn’t change the effectiveness.

  • Prescription status: Bonine is available over the counter, whereas generic Meclizine requires a prescription.

How does Bonine compare with Dramamine?

Answer:
Bonine and Dramamine are two treatments for motion sickness. Although they work similarly, there are a few key differences between them:

  • Active ingredient: Bonine contains meclizine, while Dramamine contains dimenhydrinate. Although they have different active ingredients, both work similarly to prevent motion sickness.

  • Time to take effect: Bonine takes about an hour to start working, whereas Dramamine can take effect within 30 minutes.

  • Duration of effects: Bonine can provide 24-hour relief, while Dramamine typically lasts 4-8 hours.

  • Effectiveness - Dramamine is considered more effective than Bonine at relieving motion sickness.[1]


Both treatments have advantages and drawbacks, so the choice between them depends on your preferences.

Will I get side effects using Bonine?

Answer:
Like all medicine, there's a risk of experiencing side effects when taking Bonine. Common side effects include:

  • Drowsiness

  • Tiredness

  • Headaches


The side effects should subside as your body adjusts to it. If the side effects worsen or you have any concerns, contact our doctors online.

Can I drink alcohol when taking Bonine?

Answer:
You should avoid drinking alcohol when taking Bonine. Bonine is a first-generation antihistamine, which is known for its sedative effects. Taking alcohol while on Bonine can increase drowsiness and worsen side effects.

Does Bonine cause drowsiness or sleepiness?

Answer:
Yes, Bonine is a first-generation antihistamine known for its sedative effect. First-generation antihistamines can easily cross the blood-brain barrier, and interact with the histamine receptors, making you drowsy, tired or sleepy.[2] However, meclizine is less likely to cause drowsiness compared to other first-generation antihistamines like dimenhydrinate (Dramamine).

Some people might prefer this as it helps them sleep during the journey while helping relieve motion sickness symptoms. But if you prefer a non-drowsy medicine, let your doctor know.

Is Bonine available over the counter?

Answer:
Yes, Bonine is available without a prescription from a doctor.

Treated trusted source:

  1. UC Davis (2024). Motion sickness: How you can prevent symptoms and enjoy travel. [online] cultivating-health
  2. K, Sabir S, O’Rourke MC. Antihistamines. [Updated 2023 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.

This is healthcare on your terms.

All from the comfort of your device. Get access to what you need, when you need it.

100% online

Ask questions and get expert recommendations, at the touch of a button.

Tailored choices

We'll narrow down some treatments for you to choose from based on your medical profile.

Secure shipping

Receive your treatment by express delivery, in discreet packaging.

Easy automatic refills

Set your own delivery schedule and pause or make changes any time you like.

See how it works

Your partners in health

Get to know our clinical team. They review our info, prescribe and dispense your treatments.

Dr. Joseph Palumbo

Senior Medical Adviser
Dr-Joseph

Registered with NPI (No. 1043478878)

Meet Joseph  

Dr. Rami Ahmed

Prescribing Clinician
Dr. Rami Ahmed (1)

Registered with NPI (No. 1376740092)

Meet Rami  

Mr Craig Marsh

Clinical Reviewer
Mr-Craig

Registered with GPhC (No. 2070724)

Meet Craig  

Dr Daniel Atkinson

Clinical Reviewer
Dr D,new

Registered with GMC (No. 4624794)

Meet Daniel  

Here’s what you had to say

  • Service reviews
Treated
4.45

Average rating based on 2113 reviews.

Our verification process
551

Very convenient and time saver makes things easier

A
551

Treatment is going great! Fantastic service.

T
551

Understood my needs. Worked very fast. Script showed up quickly. Very satisfied. Highly recommend.

A
551

Ordered 8/21 and arrived 8/24. Always great service.

A
551

All worked as planned.

A
551

Everything is working very well thank you so much

J
See all our reviews 

Read more about Bonine

Further reading

Woman with pink top and dark hair exercising with boxing gloves on

How to exercise safely when you have asthma

Thankfully, exercising with asthma isn’t impossible. It can take a little bit of planning, but the…

December 19, 2025 Read more
Man wearing checked shirt with glasses and grey beard in garden centre

What is an asthma attack?

Knowing the signs of an asthma attack and what to do is really important if you or someone you know …

December 19, 2025 Read more
A younger woman in a yellow cardigan sits on a couch with an older man in a blue jumper. They're both looking at a book held by the younger woman, and she's pointing to the page

Can taking weight loss injections lower your risk of getting dementia?

Everything you need to know about Wegovy and how it may lower the risk of neurodegenerative diseases…

December 12, 2025 Read more

Give us the inbox treatment.

We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.

Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.

Tell us about a problem

Accept the terms of use terms of use

What did you like about it?

What didn't you like about it?

I'm looking for
Popular searches:
Viagra Wegovy Finasteride Varenicline Zepbound