Allegra is a non-drowsy allergy relief treatment. It contains fexofenadine hydrochloride, an antihistamine that can provide relief from allergy symptoms like runny nose, sneezing, and watery eyes.
Allegra is a non-drowsy medicine that can work within one hour and can last for up to 24 hours. It’s also been found to be highly effective, with data showing it remains clinically effective even in high pollen conditions.[1]
Allergies are your body’s response to substances like pollen and dust. Your immune system reacts to these usually harmless substances, resulting in symptoms like sneezing, an itchy nose, and watery eyes. In short, Allegra helps to calm your immune response to these allergens down, and ease symptoms.
How does Allegra work?
Fexofenadine hydrochloride, the active drug in Allegra, is a second-generation antihistamine. Unlike first-generation antihistamines, it doesn’t affect the receptors in the brain, so it’s less likely to cause drowsiness.
Allergies are triggered by your immune system’s response to usually harmless substances, like pollen. This reaction causes the immune system to produce antibodies to ‘destroy’ these substances. In response, your body releases histamine, leading to allergic reactions.
Allegra is an antihistamine that binds to the histamine receptors in your body to prevent a reaction from occurring. This helps calm your immune system, providing relief from allergy symptoms.[2]
What versions of Allegra are there?
There are three different Allegra versions available. You can get Allegra 24-hour tablets containing 180 mg of fexofenadine HCL and 12-hour tablets containing 60 mg of fexofenadine HCL.Â
Allegra 24-hour relief is also available as tablets or gel caps with the same concentration.
Treated trusted source:
Allegra.com (2024). Allegra® Allergy | Official Healthcare Professional Website.
Craun KL, et al. (2024). Fexofenadine. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on September 16, 2024. Next review due on September 16, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
AllegraFexofenadine hydrochloride
How to take Allegra
Always take Allegra as prescribed by your clinician. The usual directions are:
Take one Allegra tablet with water as needed.Â
If you’re taking Allegra 24 relief tablets, don’t take more than one pill in 24 hours as this may cause side effects.Â
How long does Allegra take to work?
Allegra may take up to an hour to take effect, and reaches peak concentration between one to three hours after taking it.[1] Its effects can last 24 hours, providing all day relief from allergy symptoms.[2]
Allegra.com. (2024). Allegra® Allergy | Official Healthcare Professional Website.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on September 16, 2024. Next review due on September 16, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
AllegraFexofenadine hydrochloride
Allegra isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.Â
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
AllegraFexofenadine hydrochloride
Allegra: FAQ
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
What is the difference between Allegra and Zyrtec?
Answer:
Zyrtec is another common allergy medication. Unlike Allegra, it contains cetirizine, a different second-generation antihistamine. While both are considered non-drowsy, Zyrtec is more likely to cause drowsiness than Allegra.
In one clinical study, Zyrtec was found to be more effective than Allegra. The severity of allergy symptoms was reduced more with cetirizine (Zyrtec) than with fexofenadine (Allegra).[1]
So there are benefits to both. The treatment you choose often depends on what works best for you, taking both effectiveness and side effects into account.
Is there a generic version of Allegra available?
Answer:
Yes, a generic version of Allegra called Fexofenadine is available. Both treatments contain the same active ingredient: fexofenadine hydrochloride. The difference lies in the non-active ingredients, the concentration and the price. In terms of effectiveness, there usually isn't a significant difference, so the one you choose is up to you. However, generics are typically cheaper than the branded versions.
What is the difference between Allegra and Claritin?
Answer:
Claritin is another allergy medicine containing loratadine, a second-generation antihistamine. The main difference is that Allegra can take one hour to work compared to Claritin, which can take up to three hours.[2]
Does Allegra make you drowsy?
Answer:
Most likely, no. Allegra is a second-generation antihistamine, which typically does not cause drowsiness. However, depending on how your body reacts to it, you might experience some drowsiness.
Other common side effects include:
headache,
nausea,
dizziness.
Can you take Allegra and Benadryl together?
Answer:
While there are no interactions between the two, you shouldn’t take two antihistamines together at the same time. Taking two tablets won’t increase the effectiveness, but might increase the chances of drowsiness and other side effects.
What doses of Allegra are there?
Answer:
Allegra is available in two doses: 60mg and 180mg. Allegra 12 hour tablets contain 60 mg of fexofenadine, while Allegra 24 hour tablets contain 180 mg of fexofenadine.
If you’re not sure what dose to take, your prescriber can help you choose the one that’s likely to be more suitable for you.Â
Treated trusted source:
Day, J.H., et al (2024). Comparative efficacy of cetirizine and fexofenadine for seasonal …: Ingentaconnect.com.Â
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Sep 15, 2024
Published by: The Treated Content Team.Medically reviewed by: Dr. Joseph Palumbo, Senior Medical Adviser
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Dr. Joseph Palumbo
Senior Medical Adviser
Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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