Oxalate nephropathy

Definition:

Oxalate nephropathy is a rare condition that can lead to kidney damage and failure. It occurs when levels of a chemical called calcium oxalate become too high, causing crystals to form in the kidneys. These crystals can damage the kidney tissue.

There are two main types:

  • Primary oxalate nephropathy. This is caused by a genetic condition that leads to your body overproducing oxalate.
  • Secondary oxalate nephropathy. This is more common and can be caused by:
  • Consuming high amounts of oxalate-rich foods or supplements (like vitamin C)
  • Certain digestive conditions (like Crohn’s disease)
  • Intestinal surgery (like gastric bypass)
  • Chronic pancreatitis

Symptoms can include kidney stones, blood in your urine, painful urination, leg and ankle swelling, fatigue, loss of appetite, and vomiting and nausea. [1]

Treated trusted sources:
  1. Rosenstock, J.L., Joab, T.M.J., DeVita, M.V., Yang, Y., Sharma, P.D. and Bijol, V. (2021). Oxalate nephropathy: a review. Clinical Kidney Journal, 15(2), pp.194–204.

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